One consequence of the Spanish Conquest was the catastrophic decline in the Native American population in the?

One consequence of the Spanish Conquest was the catastrophic decline in the Native American population in the western hemisphere due to the spread of epidemic diseases.What role did the spread of disease play in the Spanish Conquest of the Aztec and Inca? How did the spread of epidemic disease affect how Native Americans responded to Spanish efforts to convert them to Christianity and to pressure them to imilate to Spanish culture after the Conquest?